Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709368 | 0.84 | ALDH1A1 (0.54) | ALDH1A1DDB1CRBN | |
| SCHEMBL21339439 | 0.80 | ALDH1A1 (0.50) | ALDH1A1DDB1CRBN | |
| SCHEMBL28554038 | 0.78 | ALDH1A1 (0.47) | ALDH1A1DDB1CRBN | |
| SCHEMBL28554039 | 0.78 | ALDH1A1 (0.47) | ALDH1A1DDB1CRBN | |
| SCHEMBL15106181 | 0.77 | ALDH1A1 (0.46) | ALDH1A1DDB1CRBN | |
| SCHEMBL18028243 | 0.77 | ALDH1A1 (0.46) | ALDH1A1DDB1CRBN | |
| SCHEMBL2028476 | 0.76 | ALDH1A1 (0.45) | ALDH1A1DDB1CRBN | |
| SCHEMBL1256462 | 0.76 | ALDH1A1 (0.51) | ALDH1A1DDB1CRBN | |
| SCHEMBL15760558 | 0.75 | ALDH1A1 (0.44) | ALDH1A1DDB1CRBN | |
| SCHEMBL19929367 | 0.75 | ALDH1A1 (0.54) | ALDH1A1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968572-B2 | Nitrogen-containing heterocyclic compound and pharmaceutical application thereof | ONO PHARMACEUTICALS CO., LTD. (JP) | 2011-06-28 | — | — | US | disclosed |