SCHEMBL6709368

SCHEMBL6709368

CC1(C)OCC(C)(C(=O)OCc2ccccc2)CO1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
DDB1 Q16531 1/20 0.46
CRBN Q96SW2 1/20 0.46
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1256462 0.89 ALDH1A1 (0.51) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL21339439 0.87 ALDH1A1 (0.50) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL28179082 0.86 ALDH1A1 (0.49) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL846827 0.85 ALDH1A1 (0.47) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL2034491 0.84 ALDH1A1 (0.50) ALDH1A1DDB1CRBN
SCHEMBL12621202 0.81 ALDH1A1 (0.53) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL18692576 0.81 ALDH1A1 (0.53) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL20599446 0.81 ALDH1A1 (0.46) ALDH1A1DDB1CRBNKMT2AMAPK1
SCHEMBL19176803 0.81 ALDH1A1 (0.50) ALDH1A1DDB1CRBNKMT2AMEN1
SCHEMBL15114589 0.80 KMT2A (0.51) ALDH1A1DDB1CRBNKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487848-A2 A BUILDING BLOCK FORMING A C=C DOUBLE BOND UPON REACTION Nuevolution A/S (DK) 2004-12-22 EP disclosed
WO-2003078445-A2 A BUILDING BLOCK FORMING A C=C DOUBLE BOND UPON REACTION NUEVOLUTION A/S (DK) 2003-09-25 WO disclosed