SCHEMBL20346129

SCHEMBL20346129

C=CC1CCC(CCc2ccc(OCCC)c(F)c2F)CC1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
KCNH2 Q12809 3/20 0.32
HTR2C P28335 3/20 0.31
HTR2B P41595 2/20 0.31
HTR2A P28223 2/20 0.31
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20346133 0.94 CNR2 (0.34) GABRA1GABRB2KCNH2CTSLCTSS
SCHEMBL20346135 0.93 GABRA1 (0.34) GABRA1GABRB2KCNH2CTSLCTSS
SCHEMBL20346128 0.91 HTR2C (0.32) HTR2CHTR2BHTR2ACTSLCTSS
SCHEMBL22277741 0.91 CNR2 (0.33) GABRA1GABRB2KCNH2
SCHEMBL22277734 0.88 HTR2A (0.30) HTR2CHTR2A
SCHEMBL15355215 0.87 KCNH2 (0.35) GABRA1GABRB2KCNH2HTR2CHTR2B
SCHEMBL9561931 0.86 KCNH2 (0.34) GABRA1GABRB2KCNH2HTR2CHTR2B
SCHEMBL9561926 0.86 KCNH2 (0.34) GABRA1GABRB2KCNH2HTR2CHTR2B
SCHEMBL20346126 0.85 SLC6A4 (0.36) KCNH2
SCHEMBL20346134 0.85 CTSL (0.33) HTR2CHTR2ACTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed