Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204508 | 0.88 | TSHR (0.46) | TLR7TLR8CXCR4 | |
| SCHEMBL211357 | 0.84 | TLR7 (0.38) | TLR7TLR8 | |
| SCHEMBL841852 | 0.81 | TLR7 (0.46) | TLR7TLR8CXCR4 | |
| Bromide SCHEMBL842506 | 0.81 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL843386 | 0.79 | TLR7 (0.41) | TLR7TLR8 | |
| Bromide SCHEMBL843477 | 0.79 | TLR7 (0.50) | TLR7TLR8 | |
| Bromide SCHEMBL842593 | 0.76 | TLR7 (0.54) | TLR7TLR8 | |
| Bromide SCHEMBL843049 | 0.76 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL5370989 | 0.76 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL843283 | 0.76 | TLR7 (0.63) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090221551-A1 | SUBSTITUTED FUSED[1,2] IMIDAZO[4,5C] RING COMPOUNDS AND METHODS | PFIZER INC. | 2009-09-03 | — | — | US | disclosed |
| WO-2007106852-A2 | SUBSTITUTED FUSED[1,2]IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221551-A1 | SUBSTITUTED FUSED[1,2] IMIDAZO[4,5C] RING COMPOUNDS AND METHODS | IL2, IFNG, IL4 | TLR7 69/4885TLR8 217/4885CXCR4 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.