Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20348350 | 1.00 | JAK2 (0.35) | JAK2JAK1JAK3CDK1CDK2 | |
| SCHEMBL20348345 | 0.98 | DPP9 (0.37) | JAK2JAK1JAK3CDK1CDK2 | |
| SCHEMBL20348349 | 0.98 | DPP9 (0.37) | JAK2JAK1JAK3CDK1CDK2 | |
| SCHEMBL20348344 | 0.97 | DPP9 (0.38) | JAK2JAK1JAK3CDK1CDK2 | |
| SCHEMBL20348360 | 0.97 | DPP9 (0.38) | JAK2JAK1JAK3CDK1CDK2 | |
| SCHEMBL20348328 | 0.86 | DPP4 (0.36) | DPP9DPP4DPP8DPP7MEN1 | |
| SCHEMBL20348332 | 0.86 | DPP4 (0.36) | DPP9DPP4DPP8DPP7MEN1 | |
| SCHEMBL25021271 | 0.84 | PDE4B (0.39) | CDK1CDK2CDK9CCNT1CCNB1 | |
| SCHEMBL20348323 | 0.84 | DPP4 (0.38) | DPP9DPP4DPP8DPP7 | |
| SCHEMBL20348338 | 0.84 | DPP4 (0.38) | DPP9DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565410-B1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| US-10246417-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018129237-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018129238-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | JAK2 4437/4885JAK1 4084/4885JAK3 3420/4885 |
| US-10246417-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | JAK2 4437/4885JAK1 4084/4885JAK3 3420/4885 |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | JAK2 4437/4885JAK1 4084/4885JAK3 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.