Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20348328 | 1.00 | DPP4 (0.36) | DPP4DPP9DPP8DPP7KDM4E | |
| SCHEMBL20348323 | 0.98 | DPP4 (0.38) | DPP4DPP9DPP8DPP7KDM4E | |
| SCHEMBL20348327 | 0.98 | DPP4 (0.38) | DPP4DPP9DPP8DPP7KDM4E | |
| SCHEMBL20348338 | 0.98 | DPP4 (0.38) | DPP4DPP9DPP8DPP7KDM4E | |
| SCHEMBL20348329 | 0.97 | DPP9 (0.39) | DPP4DPP9DPP8PYGLHTR2A | |
| SCHEMBL20348325 | 0.97 | DPP9 (0.39) | DPP4DPP9DPP8PYGLHTR2A | |
| SCHEMBL20348335 | 0.97 | DPP9 (0.39) | DPP4DPP9DPP8PYGLHTR2A | |
| SCHEMBL20348355 | 0.88 | LMNA (0.37) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL20348347 | 0.86 | JAK2 (0.35) | DPP4DPP9DPP8DPP7MEN1 | |
| SCHEMBL20348350 | 0.86 | JAK2 (0.35) | DPP4DPP9DPP8DPP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565410-B1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| US-10246417-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018129237-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018129238-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP8 202/4885 |
| US-10246417-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP8 202/4885 |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP8 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.