Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20350854 | 0.82 | KDM4E (0.65) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL20350859 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL20351062 | 0.75 | KDM4E (0.53) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL20351058 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL20339837 | 0.72 | KDM4E (0.57) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL20339858 | 0.71 | KDM4E (0.62) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL4914761 | 0.70 | TSHR (0.72) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL23183409 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL12818167 | 0.66 | ALDH1A1 (0.78) | ALDH1A1TSHRKDM4EHPGDTDP1 | |
| SCHEMBL4896857 | 0.65 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4EHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |