Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339935 | 0.83 | KDM4E (0.77) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20350859 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20351058 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20350858 | 0.75 | ALDH1A1 (0.47) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20339594 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20339496 | 0.72 | KDM4E (0.70) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20339508 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL26847329 | 0.69 | KDM4E (0.74) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL20339938 | 0.69 | KDM4E (0.74) | KDM4EALDH1A1TSHRMAPTHPGD | |
| SCHEMBL26847326 | 0.68 | KDM4E (0.59) | KDM4EALDH1A1TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |