Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | UPP1 | Q16831 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26403803 | 0.78 | TSHR (0.67) | TSHRUPP1KDM4EALDH1A1KMT2A | |
| SCHEMBL23183509 | 0.78 | MEN1 (0.48) | ATMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL26403864 | 0.77 | KDM4E (0.51) | TSHRUPP1KDM4EALDH1A1KMT2A | |
| SCHEMBL26404205 | 0.73 | KDM4E (0.48) | TSHRKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL26403952 | 0.73 | KDM4E (0.54) | TSHRKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL20340095 | 0.69 | KDM4E (0.77) | TSHRKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL26404305 | 0.68 | ALDH1A1 (0.46) | TSHRUPP1KDM4EATMALDH1A1 | |
| SCHEMBL26404220 | 0.65 | MAPT (0.51) | TSHRKDM4EATMALDH1A1KMT2A | |
| SCHEMBL26404209 | 0.65 | KDM4E (0.51) | TSHRKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL26404299 | 0.65 | MAPT (0.51) | TSHRKDM4EALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |