Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 10/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20350865 | 0.88 | ACMSD (0.45) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20340101 | 0.85 | ACMSD (0.57) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20350867 | 0.84 | KDM4E (0.50) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20350868 | 0.81 | ACMSD (0.42) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20350995 | 0.81 | ACMSD (0.47) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20350884 | 0.81 | ACMSD (0.48) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20350828 | 0.79 | ACMSD (0.40) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL23849883 | 0.79 | ACMSD (0.48) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL26847205 | 0.78 | KMT2A (0.43) | ACMSDKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20350883 | 0.78 | ALDH1A1 (0.47) | KMT2AALDH1A1HPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |