Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23183455 | 0.74 | ATM (0.54) | ATMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL20350807 | 0.71 | ATM (0.54) | ATMALDH1A1HPGDKDM4EGAA | |
| SCHEMBL20350878 | 0.67 | ATM (0.39) | ATMALDH1A1MAPTLMNAPLA2G1B | |
| SCHEMBL20339939 | 0.66 | KMT2A (0.62) | ATMALDH1A1LMNAPOLBCRHBP | |
| SCHEMBL20339404 | 0.64 | ATM (0.58) | ATMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL26847198 | 0.64 | KMT2A (0.45) | ATMALDH1A1LMNAPLA2G1BPOLB | |
| SCHEMBL20350920 | 0.63 | PIM1 (0.48) | ATMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL6193017 | 0.60 | ATM (0.69) | ATMALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL20340172 | 0.60 | ACMSD (0.61) | ALDH1A1POLBHPGDADORA2AADORA1 | |
| SCHEMBL23852913 | 0.60 | ACMSD (0.49) | ATMALDH1A1POLBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |