Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23852913 | 0.87 | ACMSD (0.49) | KMT2AMEN1POLBTNFNOD2 | |
| SCHEMBL20350857 | 0.87 | ACMSD (0.56) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL26847205 | 0.85 | KMT2A (0.43) | KMT2AMEN1POLBTNFNOD2 | |
| SCHEMBL23183542 | 0.85 | ACMSD (0.57) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL26847597 | 0.85 | ALDH1A1 (0.56) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL20340172 | 0.84 | ACMSD (0.61) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL20339582 | 0.84 | KMT2A (0.64) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL26847199 | 0.83 | ACMSD (0.48) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL24087882 | 0.82 | ACMSD (0.55) | KMT2AMEN1POLBTNFNOD2 | |
| SCHEMBL20340181 | 0.80 | KMT2A (0.42) | KMT2AMEN1POLBTNFNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | KMT2A 1353/4885MEN1 2572/4885POLB 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.