Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20352172 | 0.79 | MAPT (0.36) | MAPTHTTALDH1A1 | |
| SCHEMBL20339057 | 0.72 | PAICS (0.53) | HDAC3HDAC2KCNH2HDAC1MAPKAPK2 | |
| SCHEMBL24220431 | 0.71 | HDAC3 (0.50) | HDAC3HDAC2KCNH2HDAC1MAPKAPK2 | |
| SCHEMBL21575899 | 0.65 | MAPT (0.56) | HTR6MAPTCYP1A2CYP2C19HTT | |
| SCHEMBL14143139 | 0.62 | ADRB1 (0.51) | HTR6CYP1A2CYP2C19HTTCYP2C9 | |
| SCHEMBL25727525 | 0.62 | KDM4E (0.47) | HTR6MAPTCYP1A2CYP2C19HTT | |
| SCHEMBL1958199 | 0.62 | KDM4E (0.47) | HTR6MAPTCYP1A2CYP2C19HTT | |
| SCHEMBL24220430 | 0.61 | PIM1 (0.44) | HDAC1MAPTHTTALDH1A1CSF1R | |
| Hydrochloric Acid SCHEMBL25239609 | 0.61 | KDM4E (0.49) | HTR6MAPTCYP1A2CYP2C19HTT | |
| SCHEMBL20352035 | 0.60 | PAICS (0.67) | HDAC3HDAC2KCNH2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122549-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |