Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 11/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339057 | 0.82 | PAICS (0.53) | HDAC3HDAC2HDAC1KCNH2MAPKAPK2 | |
| SCHEMBL24220430 | 0.71 | PIM1 (0.44) | HDAC1CSF1R | |
| SCHEMBL20352018 | 0.71 | ABL1 (0.39) | HDAC3HDAC2HDAC1KCNH2MAPKAPK2 | |
| SCHEMBL20339062 | 0.70 | PAICS (0.45) | HDAC3HDAC2HDAC1KCNH2 | |
| SCHEMBL20352035 | 0.70 | PAICS (0.67) | HDAC3HDAC2HDAC1KCNH2 | |
| SCHEMBL20352118 | 0.70 | PAICS (0.54) | HDAC3HDAC2HDAC1KCNH2MAPKAPK2 | |
| SCHEMBL24220529 | 0.69 | PAICS (0.49) | HDAC3HDAC2KCNH2IRAK4 | |
| SCHEMBL20339036 | 0.69 | PAICS (0.42) | HDAC3HDAC2KCNH2 | |
| SCHEMBL20352082 | 0.67 | PAICS (0.51) | HDAC3HDAC2HDAC1KCNH2MAPKAPK2 | |
| SCHEMBL15922983 | 0.67 | HDAC3 (1.00) | HDAC3HDAC2HDAC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |