Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | PPOX | P50336 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203525 | 1.00 | MEN1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL203524 | 1.00 | MEN1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL29908511 | 0.92 | MEN1 (0.62) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL29414031 | 0.92 | MEN1 (0.62) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL29392315 | 0.92 | MEN1 (0.62) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL8187095 | 0.92 | MEN1 (0.62) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL8187092 | 0.92 | MEN1 (0.62) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10379059 | 0.90 | MEN1 (0.59) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL4099716 | 0.89 | MEN1 (0.65) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10698300 | 0.89 | TDP1 (0.67) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| US-8895471-B2 | Chiral3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1h-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihyddroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-11-25 | — | — | US | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-20130316904-A1 | Chiral3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1h-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihyddroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2013-11-28 | — | — | US | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| US-8076268-B2 | Liquid formulations containing dialkyl sulfosuccinate and hydroxyphenylpyruvate dioxygenase inhibitors | BAYER CROPSCIENCE AG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20100323894-A1 | HERBICIDAL COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-12-23 | — | — | US | disclosed |
| US-20100317517-A1 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-0860441-A1 | Herbicidal derivatives of 1,4-dithiino(2,3c)benzothiopyran | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |
| US-5633218-A | CONTROLLING WEEDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631210-A | Herbicidal thiophene ketones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0765324-A1 | CYCLIC SULFONAMIDE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1997003045-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |
| WO-1997001550-A1 | HERBICIDAL KETALS AND SPIROCYCLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |
| WO-1995033746-A1 | CYCLIC SULFONAMIDE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5446013-A | 2-alkyl-or-aryl-substituted-2-(pyrimidinyl-or-traizinyl-oxy(or-thio))-acotic acid derivatives, process for preparation, and use as herbicides or plant-growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | MEN1 2485/4885KMT2A 1733/4885TDP1 1973/4885 |
| US-20130316904-A1 | Chiral3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1h-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihyddroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulators | STS, CYP4X1, DHRS9 | MEN1 4627/4885KMT2A 1686/4885TDP1 4265/4885 |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | MEN1 4245/4885KMT2A 720/4885TDP1 1945/4885 |
| US-20100323894-A1 | HERBICIDAL COMBINATION | DDT, CYP4B1, CYP1B1 | MEN1 3308/4885KMT2A 259/4885TDP1 2643/4885 |
| US-20100317517-A1 | HERBICIDE-SAFENER COMBINATION | DDT, CIP2A, IDH2 | MEN1 3501/4885KMT2A 374/4885TDP1 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.