Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.51 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353195 | 0.82 | RAPGEF4 (0.48) | TAS1R3TAS1R1TAS1R2RAPGEF4EPHX2 | |
| SCHEMBL25039416 | 0.80 | RAPGEF4 (0.46) | RAPGEF4 | |
| SCHEMBL2094375 | 0.80 | RAPGEF4 (0.46) | TAS1R3TAS1R1TAS1R2RAPGEF4KMT2A | |
| SCHEMBL1842397 | 0.80 | RAPGEF4 (0.46) | RAPGEF4KMT2AALDH1A1MEN1 | |
| SCHEMBL22429117 | 0.79 | ALOX12 (0.57) | ALDH1A1KDM4EL3MBTL1GAALMNA | |
| SCHEMBL3976452 | 0.78 | EHMT2 (0.45) | RAPGEF4 | |
| SCHEMBL19986585 | 0.78 | LRRK2 (0.46) | KMT2AALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL8704325 | 0.77 | TP53 (0.49) | KMT2AALDH1A1KDM4EL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL8704174 | 0.76 | TP53 (0.48) | KMT2AALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL25039457 | 0.76 | RAPGEF4 (0.42) | RAPGEF4KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125569-A1 | LUBRICATING COMPOSITION INCLUDING N-ALKYLATED DIANILINE | THE LUBRIZOL CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |