Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353932 | 0.84 | ANO1 (0.60) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL20353904 | 0.81 | TP53 (0.53) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL24426964 | 0.81 | TP53 (0.51) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL20354011 | 0.80 | TP53 (0.56) | TP53ANO1MAPTRXFP1MEN1 | |
| SCHEMBL20353855 | 0.78 | ANO1 (0.68) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL8289815 | 0.78 | ANO1 (0.68) | TP53ANO1MAPTRXFP1MEN1 | |
| SCHEMBL20339110 | 0.77 | ANO1 (0.65) | TP53ANO1MAPTRXFP1FLT3 | |
| SCHEMBL20353902 | 0.77 | TP53 (0.56) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL20353959 | 0.76 | TP53 (0.63) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL20353877 | 0.76 | ANO1 (0.60) | TP53ANO1MAPTRXFP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | disclosed |