Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354011 | 0.90 | TP53 (0.56) | TP53ANO1MAPTFLT3RAB9A | |
| SCHEMBL20339093 | 0.87 | ANO1 (0.58) | TP53ANO1MAPTFLT3RAB9A | |
| SCHEMBL20353902 | 0.83 | TP53 (0.56) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20353844 | 0.83 | ANO1 (0.54) | TP53ANO1MAPTNPC1RAB9A | |
| SCHEMBL20354020 | 0.81 | TP53 (0.56) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20353927 | 0.80 | ANO1 (0.59) | TP53ANO1MAPTRAB9ARXFP1 | |
| SCHEMBL20340253 | 0.80 | ANO1 (0.59) | TP53ANO1MAPTRAB9ARXFP1 | |
| SCHEMBL20353876 | 0.80 | RAB9A (0.61) | TP53ANO1MAPTRAB9ARXFP1 | |
| SCHEMBL20353928 | 0.80 | ANO1 (0.59) | TP53ANO1MAPTRAB9ARXFP1 | |
| SCHEMBL24426964 | 0.80 | TP53 (0.51) | TP53ANO1MAPTFLT3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | disclosed |