Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339095 | 0.85 | ANO1 (0.55) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20354020 | 0.81 | TP53 (0.56) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20353904 | 0.80 | TP53 (0.53) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20354011 | 0.75 | TP53 (0.56) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20353881 | 0.74 | SMN1; SMN2 (0.53) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL24426825 | 0.74 | ANO1 (0.52) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20340274 | 0.73 | ANO1 (0.49) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20339093 | 0.73 | ANO1 (0.58) | TP53ANO1MAPTFLT3RXFP1 | |
| SCHEMBL20353932 | 0.73 | ANO1 (0.60) | TP53ANO1MAPTRXFP1THRB | |
| SCHEMBL8289815 | 0.73 | ANO1 (0.68) | TP53ANO1MAPTFLT3RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562818-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-05-18 | — | — | EP | disclosed |