SCHEMBL20354531

SCHEMBL20354531

Cc1ccc2c3ccc4c(=O)c5ccc6c7ccc8c9cc%10c%11ccc(C)c%12c%13c(C)ccc%14c%15ccc%16c(=O)c%17ccc%18c%19ccc%20c%21cc%22c%23ccc(C)c%24c1c2c1c(c%23%24)c2c%22c(c%21c9c9c%20c%19c%19c(c%109)c(c%11%12)c(c%14%13)c9c%15c%16c%17c%18c9%19)c8c7c2c2c6c5c4c3c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ESR2 Q92731 2/20 0.33
ESR1 P03372 1/20 0.33
STING1 Q86WV6 1/20 0.32
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
HCRTR1 O43613 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
AURKA O14965 1/20 0.30
DAPK3 O43293 1/20 0.30
JAK2 O60674 1/20 0.30
MAP4K4 O95819 1/20 0.30
PAK4 O96013 1/20 0.30
ABL1 P00519 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
CSF1R P07333 1/20 0.30
RET P07949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20348786 0.86 TDP2 (0.32) KDM4E
SCHEMBL20354523 0.77 CCR1 (0.30)
SCHEMBL20348792 0.72 ALDH1A1 (0.34) KDM4EESR2ALDH1A1L3MBTL1LMNA
SCHEMBL30511977 0.72 KDM4E (0.36) KDM4EALDH1A1LMNAMAPTCYP3A4
SCHEMBL26208894 0.72 KDM4E (0.36) KDM4EALDH1A1LMNAMAPTCYP3A4
SCHEMBL20354538 0.71
SCHEMBL20354584 0.71 CCR1 (0.31)
SCHEMBL29511317 0.68 ALDH1A1 (0.42) KDM4EALDH1A1L3MBTL1LMNAPOLB
SCHEMBL2779320 0.67 CYP1A2 (0.42) KDM4EESR2ESR1ALDH1A1L3MBTL1
SCHEMBL20354583 0.66 MAPT (0.36) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180185814-A1 NANOSTRUCTURED COMPOSITES FOR GAS SEPARATION AND STORAGE UNIV CALIFORNIA (US) 2018-07-05 US disclosed