Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15305716 | 0.87 | RAB9A (0.55) | NPSR1POLBNFKB1MAPTTP53 | |
| SCHEMBL11461593 | 0.85 | CYP1A2 (0.60) | NPSR1POLBMAPTTP53LMNA | |
| SCHEMBL20354983 | 0.83 | POLB (0.61) | NPSR1POLBNFKB1MAPTTP53 | |
| SCHEMBL20355107 | 0.82 | NPC1 (0.48) | NPSR1POLBNFKB1MAPTTP53 | |
| SCHEMBL20355108 | 0.82 | MAPT (0.66) | POLBMAPTTP53NPC1RAB9A | |
| SCHEMBL8798667 | 0.79 | EGFR (0.61) | NPSR1LMNARAB9AEGFR | |
| SCHEMBL691393 | 0.79 | ABCG2 (0.48) | POLBMAPTLMNANPC1RAB9A | |
| SCHEMBL20355745 | 0.77 | CYP1A2 (0.73) | NPSR1POLBNFKB1MAPTTP53 | |
| SCHEMBL29609757 | 0.76 | NUDT1 (0.58) | NPSR1POLBNFKB1MAPTTP53 | |
| SCHEMBL28736428 | 0.76 | NUDT1 (0.58) | NPSR1POLBNFKB1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122775-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2018-07-05 | — | — | WO | disclosed |