Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CBX7 | O95931 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157087 | 0.86 | KMT2A (0.45) | ALDH1A1KDM4EIDO1HPGDHTT | |
| SCHEMBL20082376 | 0.86 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EIDO1HPGDHTT | |
| SCHEMBL20355708 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EIDO1HPGDCDYL2 | |
| SCHEMBL16186530 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EIDO1HPGDCDYL2 | |
| SCHEMBL16186528 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EIDO1HPGDHTT | |
| SCHEMBL16186524 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EIDO1 | |
| SCHEMBL5283365 | 0.80 | HPGD (0.62) | ALDH1A1KDM4EIDO1HPGDHTT | |
| SCHEMBL18329422 | 0.80 | IDO1 (0.44) | ALDH1A1IDO1HPGDHTT | |
| SCHEMBL29670897 | 0.80 | IDO1 (0.44) | ALDH1A1IDO1HPGDHTT | |
| SCHEMBL20356854 | 0.80 | MEN1 (0.52) | ALDH1A1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10426784-B2 | Imidazodiazepine compound | ASTELLAS PHARMA INC. (JP) | 2019-10-01 | — | — | US | disclosed |
| US-20180185383-A1 | IMIDAZODIAZEPINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20180185383-A1 | IMIDAZODIAZEPINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185383-A1 | IMIDAZODIAZEPINE COMPOUND | HTR1D, DRD2, DRD1 | ALDH1A1 1637/4885KDM4E 2920/4885IDO1 343/4885 |
| US-10426784-B2 | Imidazodiazepine compound | GRIN2D, HTR1D, DRD2 | ALDH1A1 1063/4885KDM4E 2841/4885IDO1 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.