Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24019181 | 0.87 | MAPT (0.45) | MAPTGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL29621872 | 0.87 | MAPT (0.45) | MAPTGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL20340714 | 0.87 | MAPT (0.45) | MAPTGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL20355502 | 0.81 | MAPT (0.63) | MAPTKDM4ENPC1RAB9ATP53 | |
| SCHEMBL29621781 | 0.80 | MAPT (0.46) | MAPTGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL24019169 | 0.80 | MAPT (0.46) | MAPTGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL24019165 | 0.77 | L3MBTL1 (0.67) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20354985 | 0.76 | POLB (0.50) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL21530439 | 0.73 | ALDH1A1 (0.48) | MAPTGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL29621851 | 0.73 | ALDH1A1 (0.48) | MAPTGAAKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122775-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2018-07-05 | — | — | WO | disclosed |