SCHEMBL203565

SCHEMBL203565

C#CCOc1cc(-n2cc3c(n2)CCCC3)c(F)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPOX P50336 10/20 0.39
PGK1 P00558 1/20 0.34
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27601338 0.81 POLB (0.33) POLBTSHR
SCHEMBL27580622 0.80 POLB (0.32) POLBTSHR
SCHEMBL6438117 0.78 PPOX (0.36) PPOXPGK1LMNA
SCHEMBL10560134 0.77 PPOX (0.37) PPOXPGK1
SCHEMBL9857407 0.76 PPOX (0.35) PPOXPGK1
SCHEMBL10751373 0.75 PPOX (0.34) PPOXPGK1
SCHEMBL29448833 0.73 PPOX (0.51) PPOX
SCHEMBL314005 0.73 PPOX (0.51) PPOX
SCHEMBL18470233 0.70 PPOX (0.40) PPOXPGK1POLB
SCHEMBL9872162 0.70 PGK1 (0.40) PPOXPGK1POLBTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170041-B2 ACTIVE INGREDIENT SUSPENSIONS IN GLYCERINE BAYER CROPSCIENCE AG (DE) 2020-12-23 EP disclosed
EP-3428148-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-07-08 EP disclosed
EP-3428148-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2019-01-16 EP disclosed
EP-3088384-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF MERIAL INC (US) 2018-12-12 EP disclosed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-2373157-B1 DISPERSIONS CONTAINING HYDROXYPHENYLPYRUVATE-DIOXYGENASE INHIBITORS BAYER IP GMBH (DE) 2017-08-16 EP disclosed
EP-2167473-B1 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BAYER IP GMBH (DE) 2017-07-05 EP disclosed
EP-3088384-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2016-11-02 EP disclosed
EP-1866287-B1 SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES BAYER IP GMBH (DE) 2016-09-21 EP disclosed
EP-2155699-B9 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF MERIAL INC (US) 2016-09-14 EP disclosed
EP-0618909-A1 PYRIMIDINYL- OR TRIAZINYL-OXY(OR THIO)ALDEHYDE DERIVATIVES AND THEIR USE AS HERBICIDES OR PLANT-GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1994-10-12 EP disclosed
WO-1994013619-A1 BENZOYLCYCLOHEXENONES, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1994-06-23 WO disclosed
WO-1994010154-A1 NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1994-05-11 WO disclosed
WO-1994006778-A1 HYDROXYL AMINO PHENYL SULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1994-03-31 WO disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 EP disclosed
EP-0562510-A1 Optically active pyrimidinyl- or triazinyl-oxy-(or -thio)-carbonic acid derivatives, processes for their production and their use as herbicides or plant growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-29 EP disclosed
EP-0555770-A1 N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)-ureas, process for their preparation, and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1993-08-18 EP disclosed
WO-1993012094-A1 PYRIMIDINYL- OR TRIAZINYL-OXY(OR THIO)ALDEHYDE DERIVATIVES AND THEIR USE AS HERBICIDES OR PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1993-06-24 WO disclosed
EP-0541041-A1 Pyrimidinyl- or triazinyloxy-(or -thio)-carboxylic acids derivatives, process for their preparation and use as herbicides or plant growth regulation agents Hoechst Schering AgrEvo GmbH (DE) 1993-05-12 EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed