SCHEMBL20356905

SCHEMBL20356905

Clc1ccc2c(c1)sc1c(Cl)ncnc12

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 13/20 0.53
▸ ALDH1A1 P00352 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ GPR55 Q9Y2T6 1/20 0.45
▸ CDK5 Q00535 1/20 0.41
▸ CDK5R1 Q15078 1/20 0.41
▸ CLK1 P49759 3/20 0.41
▸ HRH4 Q9H3N8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19038471 0.87 ALDH1A1 (0.49) LIMK1ALDH1A1LMNAKMT2AGPR55
SCHEMBL7215827 0.79 LIMK1 (0.65) LIMK1LMNACDK5CDK5R1HRH4
SCHEMBL31651431 0.77 LIMK1 (0.43) LIMK1CLK1
SCHEMBL20363803 0.77 LIMK1 (0.44) LIMK1ALDH1A1LMNAKMT2ACLK1
SCHEMBL21835885 0.77 HRH4 (0.46) LIMK1ALDH1A1LMNAKMT2AHRH4
SCHEMBL25171509 0.75 BCKDK (0.39) LIMK1ALDH1A1LMNAKMT2AHRH4
SCHEMBL15223343 0.73 BCKDK (0.50) LIMK1ALDH1A1LMNAKMT2AHRH4
SCHEMBL12969548 0.73 LIMK1 (0.80) LIMK1CLK1
SCHEMBL4215069 0.72 ALDH1A1 (0.53) LIMK1ALDH1A1KMT2ACDK5
SCHEMBL20356903 0.71 LIMK1 (0.42) LIMK1CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374050-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-23 — — US disclosed
US-20230374050-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-23 — — US disclosed
US-20230374050-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-23 — — US disclosed
US-11780865-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-10 — — US disclosed
US-11780865-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-10 — — US disclosed
EP-4212540-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-19 — — EP disclosed
EP-4212540-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-19 — — EP disclosed
EP-3689890-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-03-08 — — EP disclosed
EP-3689890-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-03-08 — — EP disclosed
EP-3689890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-08-05 — — EP disclosed
EP-3689890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-08-05 — — EP disclosed
EP-3345914-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-05-13 — — EP disclosed
EP-3345914-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-05-13 — — EP disclosed
US-20180194791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 — — US disclosed
US-20180194791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 — — US disclosed
EP-3345914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-07-11 — — EP disclosed
EP-3345914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-07-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP LIMK1 1105/4885ALDH1A1 1157/4885LMNA 4106/4885
US-20230374050-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP LIMK1 1105/4885ALDH1A1 1157/4885LMNA 4106/4885
US-11780865-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP LIMK1 1105/4885ALDH1A1 1157/4885LMNA 4106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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