Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357998 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL27441049 | 0.97 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL27441054 | 0.96 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL27441051 | 0.96 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL11138247 | 0.96 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL11138248 | 0.96 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL663880 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL4756205 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL14305231 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL21457762 | 0.91 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | claimed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | claimed |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | disclosed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | XPA, MEP1A, EED | ALDH1A1 107/4885MAPT 4688/4885KDM4E 280/4885 |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | XPA, MEP1A, EED | ALDH1A1 107/4885MAPT 4688/4885KDM4E 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.