Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.58 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | IL18 | Q14116 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | PEPD | P12955 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL28194157 | 0.89 | MAPT (0.50) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL11054945 | 0.83 | MAPT (0.81) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL5062623 | 0.82 | PEPD (0.80) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL16377517 | 0.81 | PEPD (0.50) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL1548458 | 0.81 | PEPD (0.59) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL3600204 | 0.81 | MAPT (0.61) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL18132559 | 0.81 | RXFP1 (0.54) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL8044037 | 0.80 | SAE1 (0.59) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL11896322 | 0.80 | MAPT (0.65) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL7468325 | 0.79 | MAPT (0.65) | MAPTLMNATSHRHTTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014111871-A1 | 4,5-DIHYDROISOXAZOLE DERIVATIVES AS NAMPT INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-24 | — | — | WO | claimed |
| JP-4431959-B2 | — | — | 2010-03-17 | — | — | JP | claimed |
| EP-1513959-A4 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | UNIV MARYLAND AT BALTIMORE COU (US) | 2008-07-23 | — | — | EP | claimed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| JP-2005536717-A | — | — | 2005-12-02 | — | — | JP | claimed |
| EP-1513959-A2 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | University of Maryland at Baltimore County (US) | 2005-03-16 | — | — | EP | claimed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| EP-1432391-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE AND A PYRAZOLO-AZOLE COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | claimed |
| WO-2003089615-A2 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2003-10-30 | — | — | WO | claimed |
| EP-0891181-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2003-05-14 | — | — | EP | claimed |
| EP-0356925-B1 | Photographic element and process comprising a development inhibitor releasing coupler and a yellow dye-forming coupler | EASTMAN KODAK CO (US) | 1995-05-24 | — | — | EP | claimed |
| US-5116990-A | MAGENTA DYE-FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-26 | — | — | US | claimed |
| EP-0417256-A4 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS | — | 1991-09-25 | — | — | EP | claimed |
| US-5041605-A | Contacting coupler intermediate having nitro group with hydrogen donor, acylating | EASTMAN KODAK COMPANY (US) | 1991-08-20 | — | — | US | claimed |
| EP-0417256-A1 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS. | NUTRASWEET CO (US) | 1991-03-20 | — | — | EP | claimed |
| WO-1990011695-A1 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS | THE NUTRASWEET COMPANY (US) | 1990-10-18 | — | — | WO | claimed |
| EP-0356925-A2 | Photographic element and process comprising a development inhibitor releasing coupler and a yellow dye-forming coupler | EASTMAN KODAK COMPANY (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0170164-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-05 | — | — | EP | claimed |
| US-H122-H | PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1986-09-02 | — | — | US | claimed |
| EP-0170164-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-02-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | KRT18, PPOX, NOX5 | MAPT 314/4885LMNA 1642/4885TSHR 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.