Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.59 |
| ▸ | CPT1A | P50416 | 10/20 | 0.54 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | CPT2 | P23786 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636237 | 0.88 | HSD11B1 (0.66) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL1953343 | 0.85 | HSD11B1 (0.55) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL1953345 | 0.85 | HSD11B1 (0.55) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL15453437 | 0.83 | CPT1A (0.57) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL15453506 | 0.82 | TRPV1 (0.60) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL30212098 | 0.80 | TRPV1 (0.66) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL15453868 | 0.79 | CPT1A (0.46) | TRPV1CPT1ACPT1BCPT2MEN1 | |
| SCHEMBL28849366 | 0.78 | TRPV1 (0.45) | TRPV1CPT1ACPT1BCPT2MEN1 | |
| SCHEMBL2728854 | 0.77 | TRPV1 (0.46) | TRPV1CPT1ACPT1BHSD11B1CPT2 | |
| SCHEMBL17201777 | 0.77 | SMN1; SMN2 (0.46) | TRPV1CPT1ACPT1BCPT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039022-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND BODY WEIGHT RELATED DISORDERS | Baylor College Of Medicine (US) | 2016-07-06 | — | — | EP | claimed |
| WO-2015031710-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND BODY WEIGHT RELATED DISORDERS | BAYLOR COLLEGE OF MEDICINE (US) | 2015-03-05 | — | — | WO | claimed |
| EP-3039022-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND BODY WEIGHT RELATED DISORDERS | Baylor College Of Medicine (US) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015031710-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND BODY WEIGHT RELATED DISORDERS | BAYLOR COLLEGE OF MEDICINE (US) | 2015-03-05 | — | — | WO | disclosed |
| EP-2507232-A2 | PROLINE DERIVATIVES | National Health Research Institutes (TW) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068941-A2 | PROLINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-06-09 | — | — | WO | disclosed |