Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CPT1A | P50416 | 5/20 | 0.42 |
| ▸ | CPT2 | P23786 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453608 | 0.86 | SMN1; SMN2 (0.45) | TRPV1SMN1; SMN2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL28170785 | 0.82 | SMN1; SMN2 (0.48) | TRPV1SMN1; SMN2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL17201777 | 0.79 | SMN1; SMN2 (0.46) | TRPV1SMN1; SMN2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL2035962 | 0.78 | TRPV1 (0.59) | TRPV1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL28146404 | 0.77 | CYP2D6 (0.42) | — | |
| SCHEMBL1953343 | 0.75 | HSD11B1 (0.55) | TRPV1CPT1ACPT2CPT1B | |
| SCHEMBL1953345 | 0.75 | HSD11B1 (0.55) | TRPV1CPT1ACPT2CPT1B | |
| SCHEMBL27780485 | 0.72 | CPT1A (0.59) | TRPV1RAB9ANPC1CPT1ACPT2 | |
| SCHEMBL15453437 | 0.72 | CPT1A (0.57) | TRPV1CPT1ACPT2CPT1B | |
| SCHEMBL15453500 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1L3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074839-A | Composition and method for treating the metabolism illness related to body weight | 贝勒医学院 | 2017-08-18 | — | — | CN | claimed |
| CN-107074839-A | Composition and method for treating the metabolism illness related to body weight | 贝勒医学院 | 2017-08-18 | — | — | CN | disclosed |