Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.62 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.57 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094542 | 0.90 | FFAR1 (0.65) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL4653480 | 0.86 | FFAR1 (0.60) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL28835314 | 0.85 | FFAR1 (0.79) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL2774842 | 0.85 | FFAR1 (1.00) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL2171661 | 0.84 | FFAR1 (0.53) | FFAR1SRD5A2FFAR4LTA4H | |
| SCHEMBL2170992 | 0.84 | FFAR1 (0.53) | FFAR1SRD5A2FFAR4PARP10LTA4H | |
| SCHEMBL2169720 | 0.84 | F2RL1 (0.62) | FFAR1PARP10SMN1; SMN2 | |
| SCHEMBL2172243 | 0.84 | FFAR1 (0.53) | FFAR1SRD5A2FFAR4PARP10LTA4H | |
| SCHEMBL2170915 | 0.83 | FFAR1 (0.58) | FFAR1SRD5A2FFAR4PARP10LTA4H | |
| SCHEMBL2036020 | 0.83 | FFAR1 (0.76) | FFAR1FFAR4PARP10CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288669-A | Atrolactic acid amide derivative and applications thereof | UNIV NANKAI | 2013-09-11 | — | — | CN | claimed |
| CN-103288669-B | Atrolactic acid amide derivative and applications thereof | UNIV NANKAI | 2015-06-24 | — | — | CN | disclosed |
| CN-103288669-A | Atrolactic acid amide derivative and applications thereof | UNIV NANKAI | 2013-09-11 | — | — | CN | disclosed |
| EP-2349252-A2 | SYNERGISTIC COMBINATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS AND ANTIMICROTUBULE AGENTS | Exelixis, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010045580-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | EXELIXIS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045601-A2 | SYNERGISTIC EFFECTS BETWEEN SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS AND ANTIMICROTUBULE AGENTS | EXELIXIS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |