Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913491 | 0.81 | MEN1 (0.44) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 | |
| SCHEMBL1894187 | 0.79 | AKR1C3 (0.42) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 | |
| SCHEMBL6729814 | 0.75 | LMNA (0.51) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 | |
| SCHEMBL11015943 | 0.74 | CYP3A4 (0.42) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 | |
| SCHEMBL2219176 | 0.73 | TDP1 (0.59) | LMNATDP1PTGS2 | |
| SCHEMBL28013343 | 0.73 | TDP1 (0.59) | LMNATDP1PTGS2 | |
| SCHEMBL7178451 | 0.73 | FBP1 (0.38) | MEN1KMT2AAKR1C3ALDH1A1TSHR | |
| SCHEMBL28675711 | 0.73 | RECQL (0.51) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 | |
| SCHEMBL6543446 | 0.70 | CMA1 (0.44) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 | |
| SCHEMBL28878662 | 0.70 | TSHR (0.41) | MEN1KMT2ANR1I2AKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018132239-A1 | DYE-FREE NAIL VARNISH COMPOSITIONS AND METHODS THEREOF | L'OREAL (FR) | 2018-07-19 | — | — | WO | claimed |
| US-20180192758-A1 | DYE-FREE NAIL VARNISH COMPOSITIONS AND METHODS THEREOF | L'ORÉAL (FR) | 2018-07-12 | — | — | US | claimed |