⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005873 | 0.79 | — | — | |
| SCHEMBL11440982 | 0.70 | — | — | |
| SCHEMBL1164553 | 0.67 | KDM4E (0.34) | — | |
| SCHEMBL1343696 | 0.67 | KDM4E (0.34) | — | |
| SCHEMBL45941 | 0.67 | KDM4E (0.34) | — | |
| SCHEMBL6618 | 0.67 | — | — | |
| SCHEMBL4189681 | 0.65 | — | — | |
| SCHEMBL13742560 | 0.65 | — | — | |
| SCHEMBL28386367 | 0.65 | — | — | |
| Ammonia Solution, Strong SCHEMBL16007514 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053239-B2 | Compounds as BLC-2-selective apoptosis-inducing agents | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-07-06 | — | — | US | disclosed |
| US-20190345156-A1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2019-11-14 | — | — | US | disclosed |
| EP-3565815-A1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | Shanghai Fochon Pharmaceutical Co., Ltd. (CN) | 2019-11-13 | — | — | EP | disclosed |
| WO-2018127130-A1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-07-12 | — | — | WO | disclosed |