Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008854 | 0.80 | KCNN4 (0.40) | KCNN4KCNA3CYP19A1TSHRCYP3A4 | |
| SCHEMBL6923638 | 0.76 | POLB (0.47) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL15528498 | 0.76 | CYP11B1 (0.40) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL20361855 | 0.76 | CYP11B1 (0.40) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL13189778 | 0.76 | CYP11B1 (0.40) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11523600 | 0.73 | CYP11B1 (0.38) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL10236348 | 0.73 | CYP11B1 (0.38) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL28999271 | 0.73 | CYP11B1 (0.38) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL5361990 | 0.72 | CYP11B1 (0.37) | KCNN4KCNA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27815929 | 0.72 | GRN (0.37) | KCNN4KCNA3CYP11B1CYP11B2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018127096-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-07-12 | — | — | WO | disclosed |