Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189778 | 0.72 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL20360982 | 0.72 | KCNN4 (0.44) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL20361855 | 0.72 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL15528498 | 0.72 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL6923638 | 0.72 | POLB (0.47) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL10236348 | 0.69 | CYP11B1 (0.38) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL11523600 | 0.69 | CYP11B1 (0.38) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL28999271 | 0.69 | CYP11B1 (0.38) | CYP11B1CYP11B2KCNN4KCNA3MEN1 | |
| SCHEMBL4240731 | 0.69 | PTGS1 (0.41) | MAPTCYP2C9TSHRPTGS2 | |
| SCHEMBL27815929 | 0.68 | GRN (0.37) | CYP11B1CYP11B2KCNN4KCNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |