Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 13/20 | 0.63 |
| ▸ | NPY4R | P50391 | 7/20 | 0.54 |
| ▸ | NPY1R | P25929 | 5/20 | 0.54 |
| ▸ | NPY2R | P49146 | 3/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11927498 | 0.98 | OPRK1 (0.60) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL20363353 | 0.95 | OPRK1 (0.57) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL14194921 | 0.93 | OPRK1 (0.55) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22957120 | 0.93 | OPRK1 (0.54) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21286544 | 0.91 | OPRK1 (0.75) | OPRK1 | |
| SCHEMBL21286632 | 0.91 | OPRK1 (0.74) | OPRK1 | |
| SCHEMBL10316469 | 0.90 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13290888 | 0.90 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11927494 | 0.90 | OPRK1 (0.55) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL18413053 | 0.90 | OPRK1 (0.55) | OPRK1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017536-B2 | Synthetic peptide amides and dimers thereof | CARA THERAPEUTICS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017536-B2 | Synthetic peptide amides and dimers thereof | OPRK1, OPRL1, OPRM1 | OPRK1 1/4885NPY4R 46/4885NPY1R 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.