Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.69 |
| ▸ | CA9 | Q16790 | 11/20 | 0.69 |
| ▸ | CA1 | P00915 | 9/20 | 0.69 |
| ▸ | CA7 | P43166 | 5/20 | 0.69 |
| ▸ | CA6 | P23280 | 4/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.69 |
| ▸ | CA4 | P22748 | 4/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.69 |
| ▸ | CA5A | P35218 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA3 | P07451 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29641465 | 0.87 | CA12 (0.68) | CA12CA9CA1CA7CA6 | |
| SCHEMBL4890078 | 0.87 | CA12 (0.68) | CA12CA9CA1CA7CA6 | |
| SCHEMBL15510534 | 0.86 | CA12 (0.69) | CA12CA9CA1CA7CA6 | |
| SCHEMBL8869879 | 0.85 | KDM4E (0.72) | CA12CA9CA1CA7CA6 | |
| SCHEMBL12304245 | 0.85 | CA12 (0.81) | CA12CA9CA1CA7CA6 | |
| SCHEMBL19886586 | 0.84 | CA9 (0.68) | CA12CA9CA1CA7CA6 | |
| SCHEMBL7952557 | 0.83 | CA12 (0.69) | CA12CA9CA1CA7CA6 | |
| SCHEMBL29371658 | 0.82 | CA12 (0.54) | CA12CA9CA1CA7CA6 | |
| SCHEMBL6834561 | 0.82 | CA12 (1.00) | CA12CA9CA1CA7CA6 | |
| SCHEMBL8515810 | 0.82 | CA12 (1.00) | CA12CA9CA1CA7CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10780195-B2 | Controllably degradable compositions and methods | Massachusetts Instiitute of Technology (US) | 2020-09-22 | — | — | US | disclosed |
| US-20180193518-A1 | Controllably Degradable Compositions and Methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-07-12 | — | — | US | disclosed |
| US-20180193518-A1 | Controllably Degradable Compositions and Methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-07-12 | — | — | US | disclosed |