Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.69 |
| ▸ | CA9 | Q16790 | 9/20 | 0.69 |
| ▸ | CA1 | P00915 | 8/20 | 0.69 |
| ▸ | CA6 | P23280 | 4/20 | 0.69 |
| ▸ | CA7 | P43166 | 4/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.69 |
| ▸ | CA4 | P22748 | 4/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA3 | P07451 | 2/20 | 0.69 |
| ▸ | CA5A | P35218 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045405 | 0.85 | CA12 (0.82) | CA12CA9CA1CA6CA7 | |
| SCHEMBL12304245 | 0.85 | CA12 (0.81) | CA12CA9CA1CA6CA7 | |
| SCHEMBL14329540 | 0.84 | KDM4E (0.72) | CA12CA9CA1CA6CA7 | |
| SCHEMBL29862974 | 0.84 | KDM4E (0.72) | CA12CA9CA1CA6CA7 | |
| SCHEMBL11946742 | 0.84 | CA12 (0.85) | CA12CA9CA1CA6CA7 | |
| SCHEMBL31086741 | 0.83 | CA12 (0.66) | CA12CA9CA1CA6CA7 | |
| SCHEMBL15510534 | 0.83 | CA12 (0.69) | CA12CA9CA1CA6CA7 | |
| SCHEMBL20364005 | 0.83 | CA12 (0.69) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7956010 | 0.83 | CA12 (0.69) | CA12CA9CA1CA6CA7 | |
| SCHEMBL14634452 | 0.82 | CA12 (0.83) | CA12CA9CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306587-B1 | APPARATUS OF VESSEL FOR RECEIVING SAMPLE AND TWO PROBES, EACH HAVING FUNCTIONAL GROUPS CAPABLE OF REACTING WITH EACH OTHER TO FORM COVALENT BOND; LIGHT SOURCE TO ACTIVATE GROUPS; AND DETECTOR TO DETECT REACTION PRODUCT | VYSIS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-5686243-A | DETECTING POLYNUCLEOTIDE SEQUENCES; HYBRIDIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-11-11 | — | — | US | disclosed |
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0324616-A2 | Template-directed photoligation | AMOCO CORPORATION (US) | 1989-07-19 | — | — | EP | disclosed |