Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.74 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 5/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL15542572 | 1.00 | GSR (0.74) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL3213815 | 0.94 | GSR (0.77) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL27665934 | 0.93 | GSR (0.74) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL10805811 | 0.93 | GSR (0.74) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL3739868 | 0.90 | GSR (0.61) | GSRARG2ARG1RNPEPCPB2 | |
| Lysine SCHEMBL1034337 | 0.90 | GSR (0.61) | GSRARG2ARG1RNPEPCPB2 | |
| Lysine SCHEMBL9767908 | 0.88 | GSR (0.59) | GSRARG2RNPEPCPB2BLM | |
| Lysine SCHEMBL10620093 | 0.88 | GSR (0.59) | GSRRNPEPCPB2 | |
| Lysine SCHEMBL15542121 | 0.88 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL4352725 | 0.88 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10821093-B2 | Antibacterial microelement chelates and the use thereof in animal feeds | DR. BATA ZRT. (HU) | 2020-11-03 | — | — | US | disclosed |
| US-10022350-B2 | Antibacterial microelement chelates and the use thereof in animal feeds | DR. BATA ZRT. (HU) | 2018-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10022350-B2 | Antibacterial microelement chelates and the use thereof in animal feeds | SLC39A14, SLC39A3, CAT | GSR 1473/4885ARG2 123/4885ARG1 23/4885 |
| US-10821093-B2 | Antibacterial microelement chelates and the use thereof in animal feeds | SLC39A14, SLC39A3, CAT | GSR 1473/4885ARG2 123/4885ARG1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.