Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23223533 | 0.91 | MMP2 (0.62) | CTSBCAPN1MMP2ACE | |
| SCHEMBL21707852 | 0.89 | ACE (0.59) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL14623960 | 0.89 | CTSB (0.54) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL2740206 | 0.89 | CTSB (0.54) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL20204691 | 0.88 | CTSC (0.58) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL20204693 | 0.88 | CTSC (0.58) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL17521518 | 0.84 | MMP2 (0.58) | CTSBCAPN1MMP2ACECTSC | |
| SCHEMBL3497501 | 0.84 | CTSB (0.53) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL19365037 | 0.84 | CTSB (0.53) | CTSBCAPN1ACECTSCCTSL | |
| SCHEMBL17740064 | 0.83 | MMP2 (0.55) | CTSBMMP2CTSCCTSLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |