Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.67 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 14/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 9/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26181706 | 0.90 | KDM1A (0.78) | KDM1ARCOR1HSP90AB1PSMB5PSMB2 | |
| SCHEMBL22677516 | 0.85 | KDM1A (0.82) | KDM1ARCOR1PSMB5PSMB2 | |
| SCHEMBL22677537 | 0.85 | KDM1A (0.82) | KDM1ARCOR1PSMB5PSMB2 | |
| Polymyxin B3 SCHEMBL21474115 | 0.83 | KDM1A (0.91) | KDM1ARCOR1PSMB5PSMB2 | |
| Polymyxin B4 SCHEMBL21476967 | 0.83 | KDM1A (0.91) | KDM1ARCOR1PSMB5PSMB2 | |
| Polymyxin B5 SCHEMBL21258460 | 0.83 | KDM1A (0.91) | KDM1ARCOR1PSMB5PSMB2 | |
| SCHEMBL21474067 | 0.83 | KDM1A (0.80) | KDM1ARCOR1PSMB5PSMB2SSTR1 | |
| SCHEMBL21258215 | 0.82 | KDM1A (0.78) | KDM1ARCOR1HSP90AB1PSMB5PSMB2 | |
| SCHEMBL21258418 | 0.82 | KDM1A (0.81) | KDM1ARCOR1PSMB5PSMB2KEAP1 | |
| SCHEMBL21476960 | 0.81 | KDM1A (0.88) | KDM1ARCOR1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |