SCHEMBL26181706

SCHEMBL26181706

C#CCOCCOCCOCCOCCC(=O)N[C@@H](CCCCCC)C(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.78
RCOR1 Q9UKL0 2/20 0.78
TERF2IP Q9NYB0 2/20 0.40
PSMB5 P28074 8/20 0.40
PSMB2 P49721 5/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
LDHB P07195 1/20 0.39
HSP90AB1 P08238 1/20 0.39
SSTR2 P30874 4/20 0.38
SSTR1 P30872 3/20 0.38
SSTR4 P31391 3/20 0.38
SSTR3 P32745 3/20 0.38
SSTR5 P35346 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21258215 0.92 KDM1A (0.78) KDM1ARCOR1TERF2IPPSMB5PSMB2
Polymyxin B4 SCHEMBL21476967 0.91 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2
Polymyxin B3 SCHEMBL21474115 0.91 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2
Polymyxin B5 SCHEMBL21258460 0.91 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2
SCHEMBL23395792 0.91 KDM1A (0.76) KDM1ARCOR1TERF2IPKEAP1NFE2L2
SCHEMBL26181707 0.91 KDM1A (0.63) KDM1ARCOR1TERF2IPPSMB5PSMB2
SCHEMBL20366221 0.90 KDM1A (0.67) KDM1ARCOR1PSMB5PSMB2KEAP1
SCHEMBL21474116 0.90 KDM1A (0.88) KDM1ARCOR1TERF2IPPSMB5PSMB2
SCHEMBL21476960 0.90 KDM1A (0.88) KDM1ARCOR1TERF2IPPSMB5PSMB2
SCHEMBL21474118 0.90 KDM1A (0.88) KDM1ARCOR1TERF2IPPSMB5PSMB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A KDM1A 4789/4885RCOR1 4863/4885TERF2IP 4264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.