Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187400 | 0.91 | NOD1 (0.60) | NOD1MEN1GAAKMT2ASLC6A5 | |
| SCHEMBL25542921 | 0.91 | NOD1 (0.60) | NOD1MEN1GAAKMT2ASLC6A5 | |
| SCHEMBL22640886 | 0.89 | NOD1 (0.61) | NOD1MEN1GAAKMT2ASLC6A5 | |
| SCHEMBL13434505 | 0.86 | LPAR3 (0.56) | NOD1MEN1GAAKMT2ACTSS | |
| SCHEMBL20398934 | 0.86 | SLC6A5 (0.62) | NOD1MEN1GAAKMT2ASLC6A5 | |
| SCHEMBL22684548 | 0.86 | NOD1 (0.55) | NOD1MEN1GAAKMT2ASLC6A5 | |
| SCHEMBL31601080 | 0.86 | MEN1 (0.57) | NOD1MEN1GAAKMT2AEPHX2 | |
| SCHEMBL20398932 | 0.85 | SLC6A5 (0.64) | NOD1SLC6A5EPHX2GLP1R | |
| SCHEMBL20398922 | 0.85 | SLC6A5 (0.64) | NOD1SLC6A5EPHX2GLP1R | |
| SCHEMBL19809682 | 0.85 | SLC6A5 (0.64) | NOD1SLC6A5EPHX2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |