Bromide

Bromide

SCHEMBL2036664

Br.COC(=O)c1c(C)[nH]c2c(OC(=O)N3CCN(C)CC3)cc3c(c12)[C@H](CBr)CN3C(=O)C1=CC2C=C(OC)C(OC)=C(OC)C2N1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2109409 0.99
Hydrochloric Acid SCHEMBL2230505 0.99
Pibrozelesin SCHEMBL14499178 0.79 P4HB (0.44)
SCHEMBL13401608 0.76 TSHR (0.34)
SCHEMBL14012308 0.76 TSHR (0.34)
SCHEMBL13410096 0.76 HRH4 (0.34)
SCHEMBL13401541 0.73 HRH4 (0.34)
SCHEMBL14012235 0.71 HRH4 (0.45)
SCHEMBL13401447 0.70 SYK (0.39)
SCHEMBL7469393 0.70 P4HB (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
WO-2025096952-A1 SCAFFOLDS AND SCAFFOLD HOLDERS FOR TISSUE ENGINEERING UNIVERSITY OF CONNECTICUT (US) 2025-05-08 WO disclosed
EP-3086802-B1 CD44 BINDING PEPTIDES EXCHANGE IMAGING TECH GMBH (DE) 2018-09-19 EP disclosed
EP-2886126-B1 Nanoparticle conjugated to CD44 binding peptides EXCHANGE IMAGING TECH GMBH (DE) 2017-06-07 EP disclosed
US-20170073392-A1 CD44 BINDING PEPTIDES EXCHANGE IMAGING TECHNOLOGIES GMBH (DE) 2017-03-16 US disclosed
EP-3086802-A1 CD44 BINDING PEPTIDES Exchange Imaging Technologies GmbH (DE) 2016-11-02 EP disclosed
WO-2015097170-A1 CD44 BINDING PEPTIDES EXCHANGE IMAGING TECHNOLOGIES GMBH (DE) 2015-07-02 WO disclosed
EP-2886126-A1 CD44 binding peptides Endosignals Medizintechnik GmbH (DE) 2015-06-24 EP disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
WO-2011071892-A2 SURFACES FOR CONTROLLED BIOADHESION, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-06-16 WO disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US disclosed