Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331310 | 0.74 | RAC1 (0.39) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL12394014 | 0.74 | MEN1 (0.49) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL1162395 | 0.72 | CYP1A2 (0.41) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL3611240 | 0.72 | NPC1 (0.38) | CYP1A2PDE2APDE10A | |
| SCHEMBL2321107 | 0.71 | ERN1 (0.39) | CYP1A2 | |
| SCHEMBL2319119 | 0.71 | GRM8 (0.33) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL1872289 | 0.70 | NPC1 (0.37) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL2036866 | 0.69 | PDE2A (0.40) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL2318886 | 0.68 | PIK3CD (0.34) | GRM8CYP1A2GRM7PDE2APDE10A | |
| SCHEMBL25356232 | 0.67 | TAAR1 (0.47) | GRM8CYP1A2GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | disclosed |