Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CPS1 | P31327 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936514 | 0.92 | TAAR1 (0.41) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2727079 | 0.87 | TAAR1 (0.38) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2943666 | 0.86 | TAAR1 (0.44) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2938082 | 0.85 | TAAR1 (0.37) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2942699 | 0.84 | TAAR1 (0.39) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2712306 | 0.82 | TAAR1 (0.35) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2725536 | 0.82 | MAOA (0.35) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2724680 | 0.81 | MAOA (0.35) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2943945 | 0.81 | GRM8 (0.39) | TAAR1ALDH1A1CYP1A2GRM8GRM7 | |
| SCHEMBL2710047 | 0.80 | NQO2 (0.35) | TAAR1ALDH1A1CYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637438-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-20250084044-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2025-03-13 | — | — | US | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084044-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, CYP4X1, PNPO | TAAR1 3165/4885ALDH1A1 1008/4885CYP1A2 34/4885 |
| US-12637438-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, CYP4X1, CBR3 | TAAR1 3077/4885ALDH1A1 741/4885CYP1A2 63/4885 |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PPIF, CYP4X1 | TAAR1 4022/4885ALDH1A1 597/4885CYP1A2 27/4885 |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | TAAR1 4024/4885ALDH1A1 594/4885CYP1A2 27/4885 |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | TAAR1 4022/4885ALDH1A1 597/4885CYP1A2 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.