Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.30 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20370744 | 0.93 | MAPT (0.35) | MAPTHDAC1PIK3CAPI4KAPI4KB | |
| SCHEMBL20370721 | 0.90 | PIK3CA (0.38) | HDAC1PIK3CAPI4KAPI4KBFBP1 | |
| SCHEMBL20370704 | 0.88 | MAPT (0.33) | MAPTPTPN2PTPN1FBP1PTPN4 | |
| SCHEMBL20370693 | 0.88 | MAPT (0.36) | MAPTPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL20370728 | 0.86 | PIK3CA (0.38) | PIK3CAPI4KAPI4KBBACE1PIK3R1 | |
| SCHEMBL20370670 | 0.86 | PIK3CA (0.40) | PIK3CAPI4KAPI4KBDHODHBACE1 | |
| SCHEMBL20370738 | 0.81 | MAPT (0.31) | MAPT | |
| SCHEMBL20370680 | 0.80 | MEN1 (0.40) | MAPTPIK3CAPI4KAPI4KBBACE1 | |
| SCHEMBL20370688 | 0.80 | TOP1 (0.32) | MAPT | |
| SCHEMBL20370736 | 0.79 | MAPT (0.38) | MAPTPTPN2PTPN1PTPN4PTPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10854823-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-12-01 | — | — | US | disclosed |
| US-20180198074-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-07-12 | — | — | US | disclosed |
| US-20180198074-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10854823-B2 | Heterocyclic compound and organic light-emitting device including the same | CRY1, CRY2, CYP1A1 | MAPT 1408/4885HDAC1 560/4885PIK3CA 4290/4885 |
| US-20180198074-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, CYP1A1 | MAPT 1408/4885HDAC1 560/4885PIK3CA 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.