SCHEMBL203733

SCHEMBL203733

C=C(C)C(=O)OCC(O)C[O]

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
THRB P10828 1/20 0.42
ALDH1A1 P00352 3/20 0.40
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27486615 1.00 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL94906 0.89 TSHR (0.68) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL19998240 0.87 TSHR (0.65) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL9972368 0.86 TSHR (0.59) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL25707 0.83 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL137371 0.83 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL3412123 0.83 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL29375450 0.83 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL347487 0.83 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL16863053 0.83 TSHR (0.61) TSHRTHRBALDH1A1USP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
CN-115379826-B Boundary surface charged contact lens for delivery 领视药公司 2023-07-21 CN claimed
US-20230190644-A1 POROUS NANOCOMPOSITE MEDICAL IMPLANT DEVICE LYNTHERA CORPORATION 2023-06-22 US claimed
CN-115215963-B Blue light resistant cornea contact lens and preparation method thereof 江苏海伦隐形眼镜有限公司 2023-06-13 CN claimed
EP-4188331-A1 BOUNDARY SURFACE CHARGED CONTACT LENS FOR DELIVERY Lynthera Corporation (US) 2023-06-07 EP claimed
EP-4135728-A1 POROUS NANOCOMPOSITE MEDICAL IMPLANT DEVICE Lynthera Corporation (US) 2023-02-22 EP claimed
CN-115666598-A Porous nanocomposite medical implant device 领视药公司 2023-01-31 CN claimed
CN-112159505-B Medium-water-content and high-oxygen-permeability silicone hydrogel and silicone hydrogel contact lens 甘肃天后光学科技有限公司 2022-12-20 CN claimed
US-11504323-B2 Boundary surface charged contact lens for delivery LYNTHERA CORPORATION (US) 2022-11-22 US claimed
CN-115379826-A Charged contact lenses with boundary surfaces for delivery 领视药公司 2022-11-22 CN claimed
US-10617559-B2 High-precision drug delivery by dual-domain ocular device LYNTHERA CORPORATION (US) 2020-04-14 US claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
EP-3518844-A1 HIGH-PRECISION DRUG DELIVERY BY DUAL-DOMAIN OCULAR DEVICE Lynthera Corporation (US) 2019-08-07 EP claimed
US-20190224045-A1 HIGH-PRECISION DRUG DELIVERY BY DUAL-DOMAIN OCULAR DEVICE LYNTHERA CORPORATION 2019-07-25 US claimed
WO-2018064578-A1 HIGH-PRECISION DRUG DELIVERY BY DUAL-DOMAIN OCULAR DEVICE LYNTHERA CORPORATION (US) 2018-04-05 WO claimed
CN-1675252-A Macromer forming catalysts JOHNSON & JOHNSON VISION CARE (US) 2005-09-28 CN claimed
EP-0845708-B1 PLATE FOR WATERLESS LITHOGRAPHY TORAY INDUSTRIES (JP) 2003-02-12 EP claimed
US-6106997-A PRINTING DURABILITY, IMAGE REPRODUCIBILITY AND STORAGE STABILITY TORAY INDUSTRIES, INC. (JP) 2000-08-22 US claimed
EP-0845708-A1 PLATE FOR WATERLESS LITHOGRAPHY TORAY INDUSTRIES, INC. (JP) 1998-06-03 EP claimed
WO-1997001114-A1 CONTACT AND INTRAOCULAR LENSES CONTAINING ULTRAVIOLET ABSORBERS AND METHOD OF THEIR PRODUCTION ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VED C^¿ESKÉ REPUBLIKY (CZ) 1997-01-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11504323-B2 Boundary surface charged contact lens for delivery CRYZ, CLCN2, CRYAA TSHR 3947/4885THRB 4392/4885ALDH1A1 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.