Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 9/20 | 0.58 |
| ▸ | NOS3 | P29474 | 2/20 | 0.56 |
| ▸ | NOS2 | P35228 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PAH | P00439 | 1/20 | 0.46 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.39 |
| ▸ | FPGS | Q05932 | 2/20 | 0.39 |
| ▸ | GART | P22102 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374993 | 1.00 | NOS1 (0.58) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL16564267 | 0.86 | NOS1 (0.56) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL19410958 | 0.83 | NOS1 (0.59) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL188413 | 0.83 | NOS1 (0.56) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL16572892 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL20375021 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL16564323 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL1858785 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL16572891 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL16564266 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848619-B1 | METHOD FOR PRODUCING SEPIAPTERIN AND TETRAHYDROLACTOYLPTERIN | SHIRATORI PHARMACEUTICAL CO LTD (JP) | 2018-07-11 | — | — | EP | disclosed |