Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 10/20 | 0.64 |
| ▸ | CASP7 | P55210 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | PAH | P00439 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858785 | 1.00 | NOS1 (0.64) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL16572883 | 1.00 | NOS1 (0.64) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL16564266 | 1.00 | NOS1 (0.64) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL16572892 | 1.00 | NOS1 (0.64) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL16564323 | 1.00 | NOS1 (0.64) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL20375021 | 1.00 | NOS1 (0.64) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL19410958 | 0.82 | NOS1 (0.59) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL188413 | 0.82 | NOS1 (0.56) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL20375133 | 0.81 | NOS1 (0.58) | NOS1CASP7HSD17B10USP2KDM4E | |
| SCHEMBL20374993 | 0.81 | NOS1 (0.58) | NOS1CASP7HSD17B10USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181254-B2 | Method for producing sepiapterin and tetrahydrolactoylpterin | SHIRATORI PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150119574-A1 | METHOD FOR PRODUCING SEPIAPTERIN AND TETRAHYDROLACTOYLPTERIN | SHIRATORI PHARMACEUTICAL CO., LTD. (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2848619-A1 | METHOD FOR PRODUCING SEPIAPTERIN AND TETRAHYDROLACTOYLPTERIN | Shiratori Pharmaceutical Co., Ltd. (JP) | 2015-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119574-A1 | METHOD FOR PRODUCING SEPIAPTERIN AND TETRAHYDROLACTOYLPTERIN | SPR, HPN, RNPEP | NOS1 1438/4885CASP7 1605/4885HSD17B10 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.