Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614928 | 0.80 | BRD4 (0.34) | ERN1APPMAPT | |
| SCHEMBL25543621 | 0.78 | APP (0.33) | ERN1APPMAPT | |
| SCHEMBL14100633 | 0.78 | TDP1 (0.38) | MAPT | |
| SCHEMBL14627744 | 0.76 | ALDH1A1 (0.35) | ERN1APPMAPT | |
| SCHEMBL19085378 | 0.76 | PRKCI (0.34) | MAPT | |
| SCHEMBL20003980 | 0.76 | ALDH1A1 (0.44) | ERN1MAPT | |
| SCHEMBL20243902 | 0.76 | ESR1 (0.37) | APPMAPT | |
| SCHEMBL21012762 | 0.73 | TYR (0.37) | MAPT | |
| SCHEMBL21075936 | 0.73 | TRPA1 (0.35) | MAPT | |
| SCHEMBL20097295 | 0.73 | MAPT (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345907-B1 | PYRAZOLO[3,4-D]PYRIMIDINE COMPOUNDS OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-04-22 | — | — | EP | disclosed |
| EP-3345907-A1 | NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2018-07-11 | — | — | EP | disclosed |